Article
[Genetic polymorphisms of low molecular weight protein tyrosine phosphatase (LMW-PTP): relationship with erythrocyte enzymatic phenotype in patients with Systemic Lupus Erythematosus].
Acta reumatologica portuguesa - 1 Jan 2000
Esteves Martins Maria de Fátima Araújo, Carvalho Raquel, Alves Miguel, Monteiro da Silva Ferreira Carlos Alberto, Pires Bicho Manuel Diamantino
Abstract excerpt
Systemic Lupus Erythematosus (SLE) is a multisystemic autoimmune disease characterized by the loss of self-tolerance revealing defective immune regulatory mechanisms. ACP1 is a highly polymorphic erythrocyte LMW-PTP isozyme encoded by a gene presenting three alleles (A B C). These alleles determi...
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