Article
Minimizing a QTL region for intramuscular fat content by characterizing the porcine Phosphodiesterase 4B (PDE4B) gene.
BMB reports - 30 Jun 2008
Kim Jae-Hwan, Ovilo Cristina, Park Eung-Woo, Fernndez Almudena, Lee Jun-Heon, Jeon Jin-Tae, Lee Jung-Gyu
Abstract excerpt
Three isoforms of pig PDE4B were cloned and classified as two forms: PDE4B1 and PDE4B3, which contain UCR1 and UCR2; and PDE4B2, which contains only UCR2. The amino acid sequences of each isoform showed good conservation in human and rat. PDE4B2 is expressed in a wide range of tissues, but PDE4B1 and PDE4B3 are not. Using an informative SNP for the Iberian x Landrace intercross detected from intron 12, a linkage...
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