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Article

All-trans retinoic acid shifts Propionibacterium acnes-induced matrix degradation expression profile toward matrix preservation in human monocytes.

The Journal of investigative dermatology - 1 Dec 2008

Jalian H Ray, Liu Philip T, Kanchanapoomi Melissa, Phan Jenny N, Legaspi Annaliza J, Kim Jenny

Abstract excerpt

Propionibacterium acnes is a critical component in the pathogenesis of acne vulgaris, stimulating the production of various inflammatory mediators, such as cytokines and chemokines, important in the local inflammatory response found in acne. This study explored the role of P. acnes and its ability to induce matrix metalloproteinases (MMPs) in primary human monocytes and how this induction is regulated by...

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Identifiers

PMID: 18563181
DOI: 10.1038/jid.2008.155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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