Article
Models and computational strategies linking physiological response to molecular networks from large-scale data.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences - 13 Sept 2008
Ortega Fernando, Sameith Katrin, Turan Nil, Compton Russell, Trevino Victor, Vannucci Marina, Falciani Francesco
Abstract excerpt
An important area of research in systems biology involves the analysis and integration of genome-wide functional datasets. In this context, a major goal is the identification of a putative molecular network controlling physiological response from experimental data. With very fragmentary mechanistic information, this is a challenging task. A number of methods have been developed, each one with the potential to...
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