Article
Genotypic antiretroviral drug resistance testing at low viral loads in the UK.
HIV medicine - 1 Oct 2008
Cane P A, Kaye S, Smit E, Tilston P, Kirk S, Shepherd J, Hopkins M, Zhang H, Geretti A M
Abstract excerpt
BACKGROUND: Antiretroviral drug resistance testing is recommended in HIV-1 infected patients failing therapy in order to inform treatment selection. Although guidelines and test manufacturers recommend a viral load of at least 500-1000 HIV-1 RNA copies/mL for genotypic resistance testing to be performed, prompt management of virological failure could benefit from testing at lower viral load levels. METHODS:...
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