Article
Effect of the Pro12Ala polymorphism of the PPAR gamma 2 gene on response to pioglitazone treatment in menopausal women.
Menopause (New York, N.Y.) - 1 Jan 2000
Ramírez-Salazar Mónica, Pérez-Luque Elva, Fajardo-Araujo Martha, Garza Sandra Martínez, Malacara Juan Manuel
Abstract excerpt
OBJECTIVE: To investigate the influence of the Pro12Ala polymorphism of the PPAR gamma 2 gene on metabolic and hormonal response to pioglitazone treatment in obese postmenopausal women. DESIGN: We included 102 obese (body mass index [BMI] >or=30 kg/m2) and 97 nonobese (BMI <or=27 kg/m2) postmenopausal women. Anthropometric data were collected, and fasting glucose, insulin, leptin, follicle-stimulating hormone,...
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