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Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts.

Stem cells (Dayton, Ohio) - 1 Aug 2008

Mali Prashant, Ye Zhaohui, Hommond Holly H, Yu Xiaobing, Lin Jeff, Chen Guibin, Zou Jizhong, Cheng Linzhao

Abstract excerpt

It was reported recently that human fibroblasts can be reprogrammed into a pluripotent state that resembles that of human embryonic stem (hES) cells. This was achieved by ectopic expression of four genes followed by culture on mouse embryonic fibroblast (MEF) feeders under a condition favoring hE...

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Identifiers

PMID: 18511599
DOI: 10.1634/stemcells.2008-0346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18511599-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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