Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An analysis of the entire SOD1 gene in sporadic ALS.

Neuromuscular disorders : NMD - 1 Jul 2008

Luquin Natasha, Yu Bing, Trent Ronald J, Morahan Julia M, Pamphlett Roger

Abstract excerpt

Mutations in the superoxide dismutase 1 gene (SOD1) are associated with familial ALS but the role of SOD1 in sporadic ALS (SALS) is unclear. We therefore sequenced the entire SOD1 gene in 23 patients with SALS. DNA was extracted from frozen pre-frontal cerebral cortex and from blood. The 5 exons,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Amyotrophic Lateral Sclerosis
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Prefrontal Cortex

Share to Promoter Regions, Genetic

Share to Sequence Analysis, DNA

Share to Superoxide Dismutase

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 18504130
DOI: 10.1016/j.nmd.2008.04.013

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18504130-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An analysis of the entire SOD1 gene in sporadic ALS.PMID 18504130Read ↗

50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

Clinical and Molecular Landscape of ALS Patients with SOD1 Mutations: Novel Pathogenic Variants and Novel Phenotypes. A Single ALS Center Study.Semantic proximity Read ↗

Clinical characteristics of SOD1 gene mutations in UK families with ALS.Semantic proximity Read ↗

DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS.Semantic proximity Read ↗

Analysis of SOD1 mutations in a Chinese population with amyotrophic lateral sclerosis: a case-control study and literature review.Semantic proximity Read ↗

Frequency of C9orf72 and SOD1 mutations in 302 sporadic ALS patients from three German ALS centers.Semantic proximity Read ↗

Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

De novo mutations in SOD1 are a cause of ALS.Semantic proximity Read ↗

Large-scale SOD1 mutation screening provides evidence for genetic heterogeneity in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Respiratory onset of amyotrophic lateral sclerosis in a pregnant woman with a novel SOD1 mutation.Semantic proximity Read ↗

A novel exon 3 mutation (P66S) in the SOD1 gene in familial ALS.Semantic proximity Read ↗

A novel SOD1 splice site mutation associated with familial ALS revealed by SOD activity analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.