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Article

His92 and His110 selectively affect different heme centers of adrenal cytochrome b(561).

Biochimica et biophysica acta - 1 Sept 2008

Liu Wen, Rogge Corina E, da Silva Giordano F Z, Shinkarev Vladimir P, Tsai Ah-Lim, Kamensky Yury, Palmer Graham, Kulmacz Richard J

Abstract excerpt

Adrenal cytochrome b(561) (cyt b(561)), a transmembrane protein that shuttles reducing equivalents derived from ascorbate, has two heme centers with distinct spectroscopic signals and reactivity towards ascorbate. The His54/His122 and His88/His161 pairs furnish axial ligands for the hemes, but additional amino acid residues contributing to the heme centers have not been identified. A computational model of human...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18501187
DOI: 10.1016/j.bbabio.2008.04.039
PMCID: PMC2578830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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