Article
Interaction of AbrB, a transcriptional regulator from Bacillus subtilis with the promoters of the transition state-activated genes tycA and spoVG.
Molecular & general genetics : MGG - 1 Mar 1991
Fürbass R, Gocht M, Zuber P, Marahiel M A
Abstract excerpt
In Bacillus subtilis the abrB gene product negatively affects the transcription of some genes activated during the transition from vegetative to stationary phase of growth. Interaction of AbrB with the promoters of two such genes, spoVG, a sporulation gene, and tycA, an antibiotic biosynthesis gene, was studied by DNase I and hydroxyl radical footprinting. Two binding areas within the leader and promoter regions...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Base Composition
- Base Sequence
- Binding Sites
- Blotting, Western
- DNA Restriction Enzymes
- DNA, Bacterial
- DNA-Binding Proteins
- Deoxyribonuclease I