Article
[Premature ovarian failure after chemotherapy for breast cancer].
Bulletin du cancer - 1 Apr 2008
Mathelin Carole, Brettes Jean-Philippe, Diemunsch Pierre
Abstract excerpt
About a quarter of breast cancers occur before menopause. Most breast cancer types occurring in young women require adjuvant treatments that can partially or definitively affect the reproductive function. Risk factors of chemotherapy-induced ovarian failure (CIOF) include woman's age, type, dose and schedule of chemotherapy. Cyclophosphamide-based regimens, notably when high doses are used, confer the highest...
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