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Epidermal Growth Factor Inhibits Campylobacter jejuni -Induced Claudin-4 Disruption, Loss of Epithelial Barrier Function, and Escherichia coli Translocation

20 May 2008

Abstract excerpt

Campylobacter jejuni is a leading cause of acute bacterial enteritis in humans. Poultry serves as a major reservoir of C. jejuni and is thought to act as a principal vehicle of transmission to humans. Epidermal growth factor (EGF) is a small amino acid peptide that exerts a broad range of activities on the intestinal epithelium. The aims of this study were to determine the effect of EGF on C. jejuni intestinal...

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PMID: 18490463
DOI: 10.1128/iai.01698-07

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