Article
DRD3 Ser9Gly variant is not associated with essential tremor in a series of Italian patients.
European journal of neurology - 1 Sept 2008
Vitale C, Gulli R, Ciotti P, Scaglione C, Bellone E, Avanzino L, Lantieri F, Abbruzzese G, Martinelli P, Barone P, Mandich P
Abstract excerpt
BACKGROUND: Essential tremor (ET) is the most common movement disorder worldwide. Three susceptibility loci on chromosomes 3q13, 2p24.1, and 6p23 have been reported, but no causative genes were found. The Ser9Gly variant of dopamine D3 receptor (DRD3) receptor was found associated to ET in a French and US population. METHODS: A case-control study to evaluate the association between the Ser9Gly variant and ET was...
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