Article
Reappraisal of the role of the DRD3 gene in essential tremor.
Parkinsonism & related disorders - 1 Aug 2008
Blair Marcia A, Ma Shaochun, Phibbs Fenna, Fang John Y, Cooper Michael K, Davis Thomas L, Hedera Peter
Abstract excerpt
OBJECTIVES: Analyze the distribution of polymorphism in the dopamine receptor D3 (DRD3) gene, which was previously reported as a susceptibility risk for essential tremor (ET), in a large cohort of ET. METHODS: The role of 312G>A DRD3 polymorphism was analyzed using linkage analysis, association study and transmission disequilibrium test in a group of 433 ET patients, and two unrelated control groups with 121 and...
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