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Article

Relationship between sequence variation in the S1 spike protein of infectious bronchitis virus and the extent of cross‐protection<i>in vivo</i>

1 Mar 1997

Abstract excerpt

The notion that the S1 subunit of the spike glycoprotein (S) of infectious bronchitis virus (IBV) is the major inducer of protective immunity has been examined. Groups of 10 1-day-old chicks were vaccinated with isolate UK/6/82 and challenged in-tranasally 3 or 6 weeks later with strains whose S1 protein differed from that of UK/6/82 to different extents: NL/D207/79, UK/142/86 and UK/167/84 (2%), UK/123/82 (4%),...

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Identifiers

PMID: 18484262
DOI: 10.1080/03079459708419194

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