Article
A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians.
Human genetics - 1 Jul 2008
Vimaleswaran Karani S, Radha Venkatesan, Ramya Kandaswamy, Babu Hunsur Narayan Sathish, Savitha Nageshappa, Roopa Venkataramaiah, Monalisa Dhar, Deepa Raj, Ghosh Saurabh, Majumder Partha P, Rao M R Sathyanarayana, Mohan Viswanathan
Abstract excerpt
Adiponectin is an adipose tissue specific protein that is decreased in subjects with obesity and type 2 diabetes. The objective of the present study was to examine whether variants in the regulatory regions of the adiponectin gene contribute to type 2 diabetes in Asian Indians. The study comprised of 2,000 normal glucose tolerant (NGT) and 2,000 type 2 diabetic, unrelated subjects randomly selected from the...
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