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Article

Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome.

American journal of human genetics - 1 May 2008

Pezzolesi Marcus G, Platzer Petra, Waite Kristin A, Eng Charis

Abstract excerpt

Germline mutations in the gene encoding phosphatase and tensin homolog deleted on chromosome ten (PTEN [MIM 601728]) are associated with a number of clinically distinct heritable cancer syndromes, including both Cowden syndrome (CS) and Bannayan-Riley-Ruvalcaba syndrome (BRRS). Seemingly identical pathogenic PTEN mutations have been observed in patients with CS and BRRS, as well as in patients with incomplete...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18460397
DOI: 10.1016/j.ajhg.2008.04.005
PMCID: PMC2427229

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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