Dentin phosphoprotein frameshift mutations in hereditary dentin disorders and their variation patterns in normal human population

Abstract excerpt

BACKGROUND: Dentin phosphoprotein (DPP) is the most abundant non-collagenous protein in dentin, which is highly phosphorylated and plays key roles in dentin biomineralization. The aetiology of isolated hereditary dentin disorders in most affected families is largely unknown and the association between DPP and dentin disorders has not been well established. This study aims to determine whether there are some...

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