Article
Tumor necrosis factor gene polymorphisms in Turkish patients with sarcoidosis.
Internal medicine (Tokyo, Japan) - 1 Jan 2008
Seyhan Ekrem Cengiz, Cetinkaya Erdogan, Altin Sedat, Gunluoglu Zeki, Demir Adalet, Koksal Vedat, Issever Halim
Abstract excerpt
BACKGROUND: As reported recently, some gene polymorphisms are suspected to determine susceptibility to sarcoidosis and are held responsible for the extent and progression of the disease. Polymorphism at -857 locus of tumor necrosis factor (TNF)-alpha gene is considered to be a predisposition factor in sarcoidosis and held responsible for pathogenesis of the disease. We compared these polymorphisms in healthy...
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