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Gene expression profiling of single bovine embryos uncovers significant effects of in vitro maturation, fertilization and culture

30 Apr 2008

Abstract excerpt

In vitro production (IVP) has been shown to affect embryonic gene expression and often result in large offspring syndrome (LOS) in cattle and sheep. To dissect the effects of in vitro maturation, fertilization and culture on bovine embryos, we compared the expression profiles of single blastocysts generated by: (1) in vitro maturation, fertilization and culture (IVF); (2) in vivo maturation, fertilization and in...

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PMID: 18449896
DOI: 10.1002/mrd.20927

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