Article
Proteomic analysis of the winter-protected phenotype of hibernating ground squirrel intestine.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2008
Martin Sandra L, Epperson L Elaine, Rose James C, Kurtz Courtney C, Ané Cécile, Carey Hannah V
Abstract excerpt
The intestine of hibernating ground squirrels is protected against damage by ischemia-reperfusion (I/R) injury. This resistance does not depend on the low body temperature of torpor; rather, it is exhibited during natural interbout arousals that periodically return hibernating animals to euthermia. Here we use fluorescence two-dimensional difference gel electrophoresis (DIGE) to identify protein spot differences...
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