Article
Alpha-1-antitrypsin-positive "signet-ring" bile duct adenoma in a patient with M(MALTON) mutation.
International journal of surgical pathology - 1 Apr 2008
Gambarotti Marco, Medicina Daniela, Baronchelli Carla, Bercich Luisa, Bonetti Fausta, Facchetti Fabio
Abstract excerpt
A 65-year-old man with a colonic adenocarcinoma and a single small liver nodule underwent surgery. The nodule showed the histological features of a bile duct adenoma. Large eosinophilic, periodic acid-Schiff-positive diastase-resistant intracytoplasmic globules conferred a signet-ring appearance to the cells. Similar globules were found in the biliary epithelium in perinodular portal tracts, whereas smaller...
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