Article
Identification of variable simple sequence motifs in 19q13.2-qter: markers for the myotonic dystrophy locus.
Genomics - 1 Feb 1991
Smeets H J, Hermens R, Brunner H G, Ropers H H, Wieringa B
Abstract excerpt
Variable simple sequence motifs (VSSMs), or microsatellites, were used for the genetic delimitation of the myotonic dystrophy (DM) region at 19q. Three simple sequence motifs were identified in and around the ERCC1 DNA-repair gene at 19q13.2-13.3 and one in the vicinity of the RRAS gene at 19q13....
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 19
- Crossing Over, Genetic
- DNA Repair
- Female
- Genetic Linkage
- Genetic Markers
- Haplotypes
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Myotonic Dystrophy
- Pedigree
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping