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Article

Differential Gene Expression Changes in Children with Severe Dengue Virus Infections

8 Apr 2008

Abstract excerpt

BACKGROUND: The host response to dengue virus infection is characterized by the production of numerous cytokines, but the overall picture appears to be complex. It has been suggested that a balance may be involved between protective and pathologic immune responses. This study aimed to define differential immune responses in association with clinical outcomes by gene expression profiling of a selected panel of...

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PMID: 18398488
DOI: 10.1371/journal.pntd.0000215

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