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Article

Clinical, neuropathological and genotypic variability in SNCA A53T familial Parkinson's disease. Variability in familial Parkinson's disease.

Acta neuropathologica - 1 Jul 2008

Markopoulou K, Dickson D W, McComb R D, Wszolek Z K, Katechalidou L, Avery L, Stansbury M S, Chase B A

Abstract excerpt

Individuals with familial Parkinson's disease (PD) due to a monogenic defect can show considerable clinical and neuropathological variability. To identify factors underlying this variability, histopathological analysis was performed in two clinically different A53T alpha-synuclein heterozygotes f...

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Identifiers

PMID: 18389263
DOI: 10.1007/s00401-008-0372-4
PMCID: PMC2728685

Genes

SNCA

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18389263-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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