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Article

Genes regulating the serotonin metabolic pathway in the brain stem and their role in the etiopathogenesis of the sudden infant death syndrome.

Genomics - 1 Jun 2008

Nonnis Marzano Francesco, Maldini Milena, Filonzi Laura, Lavezzi Anna Maria, Parmigiani Stefano, Magnani Cinzia, Bevilacqua Giulio, Matturri Luigi

Abstract excerpt

Genotypes and allelic frequencies of TPH2, 5-HTTLPR, the 5-HTT (SLC6A4) intron 2 variable-number tandem repeat (VNTR) region, and the MAOA VNTR region were determined in brain-stem samples of 20 "genuine" SIDS cases and compared with results obtained from 150 healthy controls. The SNP G1463A responsible for 80% functionality loss of TPH2 (tryptophan hydroxylase 2) was not detected, neither in SIDS infants nor in...

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Source

Identifiers

PMID: 18387780
DOI: 10.1016/j.ygeno.2008.01.010

Genes

MAOA
TPH2
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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