Article
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Kähler Anna K, Djurovic Srdjan, Kulle Bettina, Jönsson Erik G, Agartz Ingrid, Hall Håkan, Opjordsmoen Stein, Jakobsen Klaus D, Hansen Thomas, Melle Ingrid, Werge Thomas, Steen Vidar M, Andreassen Ole A
Abstract excerpt
Several lines of evidence support the theory of schizophrenia (SZ) being a neurodevelopmental disorder. The structural, cytoarchitectural and functional brain abnormalities reported in patients with SZ, might be due to aberrant neuronal migration, since the final position of neurons affects neuronal function, morphology, and formation of synaptic connections. We have investigated the putative association between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.