Article
Interleukin-6 (-174C) polymorphism and the risk of sepsis in very low birth weight infants: meta-analysis.
Archives of disease in childhood. Fetal and neonatal edition - 1 Nov 2008
Chauhan M, McGuire W
Abstract excerpt
BACKGROUND: The guanidine to cytosine transition at position -174 nucleotides relative to the transcription start site in the interleukin (IL)-6 gene has been implicated as a genetic risk factor for the development of sepsis in very low birth weight (VLBW) infants. However, association studies have reported conflicting findings and have generally been underpowered to exclude modest effect sizes. AIM: To...
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