Absence of motilin gene mutations in infantile hypertrophic pyloric stenosis.

Abstract excerpt

BACKGROUND: Erythromycin treatment before 2 weeks of age has been shown to increase the risk of infantile hypertrophic pyloric stenosis (IHPS) up to 10 times. Erythromycin is a motilin agonist, a hormone that induces gastrointestinal contractions. The purpose of this study was to investigate if mutations in the motilin gene (MLN) cause IHPS or if the V15A polymorphism in MLN is associated with the disease....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Case-Control Studies
• Share to Gastrointestinal Motility