Article
Analysis of caprine pituitary specific transcription factor-1 gene polymorphism in indigenous Chinese goats.
Molecular biology reports - 1 Apr 2009
Lan X Y, Li M J, Chen H, Zhang L Z, Jing Y J, Wei T B, Ren G, Wang X, Fang X T, Zhang C L, Lei C Z
Abstract excerpt
Since mutations on POU1F1 gene possibly resulted in deficiency of GH, PRL, TSH and POU1F1, this study revealed the polymorphism of goat POU1F1-AluI locus and analyzed the distribution of alleles on 13 indigenous Chinese goat breeds. The PCR-RFLP analysis showed the predominance of TT genotype and the frequencies of allele T varied from 0.757 to 0.976 in the analyzed populations (SBWC, Bo, XH and HM). Further...
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