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Article

Evaluation of Apolipoprotein M Serum Concentration as a Biomarker of HNF-1alpha MODY

1 Jan 2007

Abstract excerpt

Apolipoprotein M (apoM) is a 26-kDa protein expressed mainly in the liver and kidneys. It is present predominantly in high-density lipoproteins (HDL). ApoM expression is influenced by the hepatocyte nuclear factor-1alpha (HNF-1alpha), which is a transcription factor associated with the pathogenesis of MODY. Some earlier data suggested that apoM levels were lower in the serum of HNF-1alpha MODY subjects, than in...

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Identifiers

PMID: 18338076
DOI: 10.1900/rds.2007.4.231

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