Article
A systematic forward genetic analysis identified components of the Chlamydomonas circadian system.
Genes & development - 1 Apr 2008
Matsuo Takuya, Okamoto Kazuhisa, Onai Kiyoshi, Niwa Yoshimi, Shimogawara Kosuke, Ishiura Masahiro
Abstract excerpt
The molecular bases of circadian clocks have been studied in animals, fungi, bacteria, and plants, but not in eukaryotic algae. To establish a new model for molecular analysis of the circadian clock, here we identified a large number of components of the circadian system in the eukaryotic unicellular alga Chlamydomonas reinhardtii by a systematic forward genetic approach. We isolated 105 insertional mutants that...
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