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Article

Heritability and intrafamilial aggregation of arterial characteristics.

Journal of hypertension - 1 Apr 2008

Seidlerová Jitka, Bochud Murielle, Staessen Jan A, Cwynar Marcin, Dolejsová Milena, Kuznetsova Tatiana, Nawrot Tim, Olszanecka Agnieszka, Stolarz Katarzyna, Thijs Lutgarde, Wojciechowska Wiktoria, Struijker-Boudier Harry A, Kawecka-Jaszcz Kalina, Elston Robert C, Fagard Robert, Filipovský Jan

Abstract excerpt

BACKGROUND: We investigated the heritability and familial aggregation of various indexes of arterial stiffness and wave reflection and we partitioned the phenotypic correlation between these traits into shared genetic and environmental components. METHODS: Using a family-based population sample, we recruited 204 parents (mean age, 51.7 years) and 290 offspring (29.4 years) from the population in Cracow, Poland...

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PMID: 18327082
DOI: 10.1097/HJH.0b013e3282f4d1e7
PMCID: PMC3693934

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