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Article

The impact of mitochondrial tRNA mutations on the amount of ATP synthase differs in the brain compared to other tissues.

Biochimica et biophysica acta - 1 May 2008

Fornuskova Daniela, Brantova Olga, Tesarova Marketa, Stiburek Lukas, Honzik Tomas, Wenchich Laszlo, Tietzeova Evzenie, Hansikova Hana, Zeman Jiri

Abstract excerpt

The impact of point mutations in mitochondrial tRNA genes on the amount and stability of respiratory chain complexes and ATP synthase (OXPHOS) has been broadly characterized in cultured skin fibroblasts, skeletal muscle samples, and mitochondrial cybrids. However, less is known about how these mutations affect other tissues, especially the brain. We have compared OXPHOS protein deficiency patterns in skeletal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mitochondrial Proton-Translocating ATPases

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Share to Oxidative Phosphorylation

Share to Oxygen Consumption

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Source

Identifiers

PMID: 18319067
DOI: 10.1016/j.bbadis.2008.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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