Article
Twitching motility is essential for virulence in Dichelobacter nodosus.
Journal of bacteriology - 1 May 2008
Han Xiaoyan, Kennan Ruth M, Davies John K, Reddacliff Leslie A, Dhungyel Om P, Whittington Richard J, Turnbull Lynne, Whitchurch Cynthia B, Rood Julian I
Abstract excerpt
Type IV fimbriae are essential virulence factors of Dichelobacter nodosus, the principal causative agent of ovine foot rot. The fimA fimbrial subunit gene is required for virulence, but fimA mutants exhibit several phenotypic changes and it is not certain if the effects on virulence result from the loss of type IV fimbria-mediated twitching motility, cell adherence, or reduced protease secretion. We showed that...
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