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Article

On the testing load incurred by cascade genetic carrier screening for Mendelian disorders: a brief report.

Genetic testing - 1 Jan 2007

Krawczak Michael, Caliebe Amke, Croucher Peter J P, Schmidtke Jörg

Abstract excerpt

One criterion to decide to whom molecular genetic carrier testing should be provided is an individual's carrier risk, taking into account his or her affection status and degree of relatedness to an overt carrier. We have derived formulas to calculate the testing load incurred to a public health system following such a cascade screening strategy. While the testing load turns out to be moderate for individual...

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Identifiers

PMID: 18294059
DOI: 10.1089/gte.2007.0028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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