Article
Biogenesis of Fe/S proteins and pathogenicity: IscR plays a key role in allowing Erwinia chrysanthemi to adapt to hostile conditions.
Molecular microbiology - 1 Mar 2008
Rincon-Enriquez Gabriel, Crété Patrice, Barras Frédéric, Py Béatrice
Abstract excerpt
The Erwinia chrysanthemi genome is predicted to encode three systems, Nif, Isc and Suf, known to assist Fe/S cluster biogenesis and the CsdAE cysteine desulphurase. Single iscU, hscA and fdx mutants were found sensitive to paraquat and exhibited reduced virulence on both chicory leaves and Arabidopsis thaliana. Depletion of the whole Isc system led to a pleiotropic phenotype, including sensitivity to both...
Topics
- Adaptation, Physiological
- Arabidopsis
- Bacterial Proteins
- Carbon-Sulfur Lyases
- Cichorium intybus
- Chromosomes, Bacterial
- Dickeya chrysanthemi
- Gene Expression Regulation, Bacterial
- Genome, Bacterial
- Iron-Sulfur Proteins
- Models, Genetic
- Mutation
- Operon
- Paraquat
- Phenotype
- Plant Leaves
- Virulence