Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.

Human reproduction (Oxford, England) - 1 Apr 2008

Kristensen David M, Nielsen John E, Skakkebaek Niels E, Graem Niels, Jacobsen Grete K, Rajpert-De Meyts Ewa, Leffers Henrik

Abstract excerpt

BACKGROUND: UTF-1 and REX-1/ZFP42 are transcription factors involved in pluripotency. Because of phenotypic similarities between pluripotent embryonic stem cells and testicular germ cell tumours (TGCT) and the derivation of pluripotent cells from testes, we investigated the expression of UTF-1 and REX-1 during human gonadal development and in TGCT. METHODS: Expression of UTF-1 and REX-1 was studied in 52...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation, Neoplastic
Share to Gestational Age

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Kruppel-Like Transcription Factors

Share to Neoplasms, Germ Cell and Embryonal

Share to Testis

Share to Trans-Activators

Source

Identifiers

PMID: 18281244
DOI: 10.1093/humrep/den010

Genes

NANOG
ZFP42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.PMID 18281244Read ↗

A Distinct Expression Pattern in Mammalian Testes Indicates a Conserved Role for NANOG in SpermatogenesisSemantic proximity Read ↗

Chromosome X-encoded cancer/testis antigens show distinctive expression patterns in developing gonads and in testicular seminomaSemantic proximity Read ↗

Novel germ cell markers characterize testicular seminoma and fetal testisSemantic proximity Read ↗

The pluripotency homeobox gene <i>NANOG</i> is expressed in human germ cell tumorsSemantic proximity Read ↗

Pluripotency of spermatogonial stem cells from adult mouse testisSemantic proximity Read ↗

Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumoursSemantic proximity Read ↗

Expression of pluripotent stem cell markers in the human fetal ovarySemantic proximity Read ↗

Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma <i>in situ</i> and germ cell tumoursSemantic proximity Read ↗

UTF1, a Putative Marker for Spermatogonial Stem Cells in StallionsSemantic proximity Read ↗

Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.