Article
Predicting RNA-binding sites from the protein structure based on electrostatics, evolution and geometry.
Nucleic acids research - 1 Mar 2008
Chen Yao Chi, Lim Carmay
Abstract excerpt
An RNA-binding protein places a surface helix, beta-ribbon, or loop in an RNA helix groove and/or uses a cavity to accommodate unstacked bases. Hence, our strategy for predicting RNA-binding residues is based on detecting a surface patch and a disparate cleft. These were generated and scored acco...
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