Article
Alteration of apparent negative cooperativity of ATPase activity by alpha-subunit glutamine 173 mutation in yeast mitochondrial F1. Correlation with impaired nucleotide interaction at a regulatory site.
The Journal of biological chemistry - 5 May 1991
Jault J M, Di Pietro A, Falson P, Gautheron D C
Abstract excerpt
The first described alpha-subunit mutation of yeast mitochondrial F1 has been recently identified as a single Gln173----Leu substitution in a strongly conserved sequence (Falson, P., Maffey, L., Conrath, K., and Boutry, M. (1991) J. Biol. Chem. 266, 287-293). This mutation is shown here to greatl...
Topics
- Adenosine
- Adenosine Triphosphatases
- Affinity Labels
- Amino Acid Sequence
- Azides
- Bicarbonates
- Enzyme Activation
- Glutamine
- Guanosine
- Hydrogen-Ion Concentration
- Hydrolysis
- Kinetics
- Mitochondria
- Molecular Sequence Data
- Mutation
- Proton-Translocating ATPases
- Schizosaccharomyces
- Temperature