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Assessment of glycosaminoglycan concentration <i>in vivo</i> by chemical exchange-dependent saturation transfer (gagCEST)

11 Feb 2008

Abstract excerpt

Glycosaminogycans (GAGs) are involved in numerous vital functions in the human body. Mapping the GAG concentration in vivo is desirable for the diagnosis and monitoring of a number of diseases such as osteoarthritis, which affects millions of individuals. GAG loss in cartilage is typically an initiating event in osteoarthritis. Another widespread pathology related to GAG is intervertebral disk degeneration....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18268341
DOI: 10.1073/pnas.0707666105

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