Article
Apolipoprotein E-polymorphism, frailty and mortality in older adults.
Journal of cellular and molecular medicine - 1 Dec 2008
Rockwood Kenneth, Nassar Bassam, Mitnitski Arnold
Abstract excerpt
Although apolipoprotein E (ApoE) polymorphism is associated with variable risks of several illnesses, and with mortality, no persuasive relationship has been demonstrated with frailty. Here, the clinical examination cohort (n=1452 older adults, aged 70+ years at baseline) of the Canadian Study of Health and Aging was evaluated, with 5-year follow-up data. Frailty was defined using both the phenotypic definition...
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