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Article

X-linked nonsyndromic sinus node dysfunction and atrial fibrillation caused by emerin mutation.

Journal of cardiovascular electrophysiology - 1 May 2008

Karst Margaret L, Herron Kathleen J, Olson Timothy M

Abstract excerpt

INTRODUCTION: Atrial fibrillation (AF) is a heritable disorder with male predilection, suggesting a sex chromosome defect in certain patients. Loss-of-function truncation mutations in EMD, encoding the nuclear membrane protein emerin, cause X-linked Emery-Dreifuss muscular dystrophy (EDMD) characterized by localized contractures and skeletal myopathy in adolescence, sinus node dysfunction (SND) in early...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18266676
DOI: 10.1111/j.1540-8167.2007.01081.x
PMCID: PMC2367157

Genes

EMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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