Article
Plasma PAI-1 levels are independently related to fatty liver and hypertriglyceridemia in familial combined hyperlipidemia, involvement of apolipoprotein E.
Thrombosis research - 1 Jan 2008
Brouwers Martijn C G J, Govers-Riemslag Jose, Schalkwijk Casper G, van Greevenbroek Marleen M J, van der Kallen Carla J H, Bekers Otto, van Dieijen-Visser Marja P, Ten Oever Jaap, Bilderbeek-Beckers Monique A L, de Bruin Tjerk W A, Ten Cate Hugo, Stehouwer Coen D A
Abstract excerpt
BACKGROUND: Familial combined hyperlipidemia (FCHL) is a genetic form of dyslipidemia, which is characterized by an increased cardiovascular risk. The current study was conducted to investigate the relation of endothelial, inflammatory and fibrinolysis markers with the presence of hypertriglyceridemia and fatty liver in FCHL, in order to advance insight in their contribution to the cardiovascular risk profile....
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