Article
Construction of infectious cDNA clones of PRRSV: separation of coding regions for nonstructural and structural proteins.
Science in China. Series C, Life sciences - 1 Mar 2008
Yuan ShiShan, Wei ZuZhang
Abstract excerpt
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), the causative agent of the ongoing "porcine high fever syndrome" in China, is capable of genetic and antigenic mutations at high frequency. How to design vaccine rationally to keep up with the ever-changing prevalent PRRSV variant is of great interest. We developed an infectious cDNA clone of an attenuated strain of Type II PRRSV, and further...
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