Article
Gefitinib (ZD1839): therapy in selected patients with non-small cell lung cancer (NSCLC)?
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2008
Dongiovanni Diego, Daniele Lorenzo, Barone Carla, Dongiovanni Vincenzo, Fissore Camilla, Sapino Anna, Macrì Luigia, Bussolati Giovanni, Buffoni Lucio, Gaspari Fabio, Grillo Raffaella, Birocco Nadia, Addeo Alfredo, Ciuffreda Libero, Schena Marina
Abstract excerpt
PURPOSE: To evaluate response rate, toxicity and epidermal growth factor (EGFR) mutations and gene copy number as outcome predictive factors in Italian patients with non-small cell lung cancer (NSCLC) treated with gefitinib (Iressa) in an expanded access program (EAP). PATIENTS AND METHODS: A total of 137 patients with advanced NSCLC received gefitinib as first line treatment or after failure of chemotherapy. In...
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