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Article

Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy.

Neuroscience letters - 5 Mar 2008

Holland Katherine D, Kearney Jennifer A, Glauser Tracy A, Buck Gerri, Keddache Mehdi, Blankston John R, Glaaser Ian W, Kass Robert S, Meisler Miriam H

Abstract excerpt

Mutations in the sodium channel genes SCN1A and SCN2A have been identified in monogenic childhood epilepsies, but SCN3A has not previously been investigated as a candidate gene for epilepsy. We screened a consecutive cohort of 18 children with cryptogenic partial epilepsy that was classified as pharmacoresistant because of nonresponse to carbamazepine or oxcarbazepine, antiepileptic drugs that bind sodium...

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Identifiers

PMID: 18242854
DOI: 10.1016/j.neulet.2007.12.064
PMCID: PMC2423278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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