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Article

Single nucleotide polymorphism C/T(-13910), located upstream of the lactase gene, associated with adult-type hypolactasia: validation for clinical practice.

Clinical biochemistry - 1 May 2008

Mattar Rejane, Monteiro Maria do Socorro, Villares Cibele Aparecida, dos Santos Aníbal Ferreira, Carrilho Flair José

Abstract excerpt

OBJECTIVES: To validate C/T(-13910) polymorphism associated with primary hypolactasia for clinical practice. DESIGN AND METHODS: Lactose breath test and PCR-RFLP for the C/T(-13910) polymorphism were performed. RESULTS: Twenty-seven of 28 patients with genotype CC had positive breath tests; all twenty-two patients with genotypes CT or TT had negative breath tests. Agreement of tests was high (p<0.0001; Kappa...

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Identifiers

PMID: 18237552
DOI: 10.1016/j.clinbiochem.2008.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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