Article
A functional anti-mullerian hormone gene polymorphism is associated with follicle number and androgen levels in polycystic ovary syndrome patients.
The Journal of clinical endocrinology and metabolism - 1 Apr 2008
Kevenaar Marlies E, Laven Joop S E, Fong Sharon Lie, Uitterlinden André G, de Jong Frank H, Themmen Axel P N, Visser Jenny A
Abstract excerpt
CONTEXT: The common characteristic of polycystic ovary syndrome (PCOS) is a disturbance in the selection of the dominant follicle, resulting in anovulation. In PCOS women, serum anti-Müllerian hormone (AMH) levels are elevated. Because AMH decreases FSH sensitivity in mice, the elevated AMH levels may contribute to the disturbed follicle selection in PCOS women. OBJECTIVE: The objective of the study was to...
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