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Article

Genotyping reveals a wide heterogeneity of Tropheryma whipplei.

Microbiology (Reading, England) - 1 Feb 2008

Li Wenjun, Fenollar Florence, Rolain Jean-Marc, Fournier Pierre-Edouard, Feurle Gerhard E, Müller Christian, Moos Verena, Marth Thomas, Altwegg Martin, Calligaris-Maibach Romana C, Schneider Thomas, Biagi Federico, La Scola Bernard, Raoult Didier

Abstract excerpt

Tropheryma whipplei, the causative agent of Whipple's disease, is associated with various clinical manifestations as well as an asymptomatic carrier status, and it exhibits genetic heterogeneity. However, relationships that may exist between environmental and clinical strains are unknown. Herein, we developed an efficient genotyping system based on four highly variable genomic sequences (HVGSs) selected on the...

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PMID: 18227256
DOI: 10.1099/mic.0.2007/011668-0

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